CASK (Calcium/calmodulin-dependent serine protein kinase gene)

About CASK

Calcium/calmodulin-dependent serine protein kinase (CASK) is a protein that helps tissues grow and communicate between cells. In muscles, it helps make connections between nerves and muscles. When pigeons race, it causes continuous changes in their muscles. In most pigeon species including rock pigeons, we see the normal wild-type CASKGG. In racing pigeons, a CASK(A) mutation was found that can be associated with a functional change. Racing pigeons with this CASK(A) mutation are said to have better flight ability. A double mutation CASK(AA) is very interesting for breeding pigeons.

Suitable samples

Feathers

  • One set of 4-5 freshly plucked breast feathers or 2-3 tail or wing feathers
  • Fallen moulting feathers, down feathers and blood feathers should be avoided. These sometimes contain insufficient DNA or can cause damage to the feather follicle when pulled out. 
  • Blood feathers are the new feathers that can be recognised by the blue sleeve at the base of the plume.
  • To avoid contamination, the shaft (the end of the feather that comes out of the bird's skin) must not be touched with the hands

Blood sample

  • Small amounts (capillary tube) are sufficient for accurate analysis

Cheek swab of a nestling

  • A gentle way to collect DNA from young birds
  • Caution: avoid mixing with food or food waste

Results

  • Processing time 2-3 working days
  • You will receive an email when your results and certificate are available on your personal portal